Resistance to Antibiotics

Phenotypic Resistance to Antibiotics

The development of antibiotic resistance is usually associated with genetic changes, either to the acquisition of resistance genes, or to mutations in elements relevant for the activity of the antibiotic. However, in some situations resistance can be achieved without any genetic alteration; this is called phenotypic resistance. Non-inherited resistance is associated to specific processes such a...

Resistance to antibiotics.

Propionibacterial resistance to antibiotics in patients with Acne Vulgaris

Background: Acne vulgaris is a self-limited disease that mainly involves the sebaceous follicles. Systemic antibiotic is a common therapeutic modality, so bacterial resistance can be a problem. Objectives: Assessment of Propionibacterium resistance to erythromycin, tetracycline, clindamycin and spiramycin. Patients and Methods: Sampling was done on lesions of 123 patients with acne vulgaris who...

Development of Resistance to Antibiotics

Widespread use and misuse of penicillin and other antibiotics have resulted in development of resistance most antibiotics. The mechanisms by which microorganisms develop resistance to antibiotics are discussed. Topics covered include acquisition of point mutations and antibiotic resistance genes, methods of transfer of resistance genes between bacteria, and the advantages of synthetic antibioti...

Studies on Resistance to Antibiotics

The discovery of gramicidin, penicillin, streptomycin, and the numerous other antibiotics known today has contributed materially to the list of therapeutic agents available against micro-organisms. However, the immediate enthusiasm which greeted their introduction has had to be checked by the realization that many of the important organisms affected readily develop resistance to the antibiotic ...